SCHEMBL31294885

SCHEMBL31294885

CN1C(=O)C(C)(F)c2c(Cl)cccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.43
HTT P42858 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
PGR P06401 1/20 0.38
DRD2 P14416 1/20 0.38
DRD3 P35462 1/20 0.38
NOTUM Q6P988 2/20 0.36
HCRTR1 O43613 1/20 0.35
AKR1B1 P15121 1/20 0.35
MGLL Q99685 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
IDO1 P14902 1/20 0.34
KAT2B Q92831 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31294874 0.77 TDP1 (0.35) HTTKDM4ELMNAMAPTALDH1A1
SCHEMBL31294858 0.73 MAPT (0.53) HTTKDM4ELMNAMAPTALDH1A1
SCHEMBL28158684 0.68 NOTUM (0.37) RECQLHTTKDM4ELMNAMAPT
SCHEMBL30082327 0.67 MGLL (0.39) HTTKDM4ELMNAMAPTALDH1A1
SCHEMBL19704112 0.67 MGLL (0.39) HTTKDM4ELMNAMAPTALDH1A1
SCHEMBL28683717 0.66 HTT (0.35) RECQLHTTKDM4ELMNAMAPT
SCHEMBL28050747 0.66 OPRM1 (0.44) RECQLHTTKDM4ELMNAMAPT
SCHEMBL24866846 0.66 MGLL (0.41) HTTKDM4ELMNAMAPTALDH1A1
SCHEMBL9591238 0.65 LMNA (0.50) HTTKDM4ELMNAMAPTALDH1A1
SCHEMBL21726268 0.64 FAAH (0.41) HTTKDM4ELMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119118900-B Method for synthesizing 3-fluorooxindole compound by visible light catalysis NANJING TECH UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-119118900-A Method for synthesizing 3-fluorooxindole compound by visible light catalysis 南京工业大学 2024-12-13 CN disclosed