Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968478 | 0.69 | ACHE (0.43) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL544039 | 0.66 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8969378 | 0.64 | ACHE (0.46) | — | |
| SCHEMBL11847844 | 0.63 | MAPK1 (0.36) | ALDH1A1 | |
| SCHEMBL11564815 | 0.63 | MAPT (0.44) | — | |
| SCHEMBL544414 | 0.61 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8969272 | 0.61 | ACHE (0.54) | ALDH1A1HPGD | |
| SCHEMBL8969165 | 0.61 | — | — | |
| SCHEMBL8969659 | 0.58 | — | — | |
| SCHEMBL11328547 | 0.57 | HCAR2 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |