Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | GLA | P06280 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969989 | 0.84 | MAPT (0.44) | MAPT | |
| SCHEMBL8969246 | 0.81 | ALDH1A1 (0.47) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL8969928 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL8969448 | 0.80 | ACHE (0.37) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL8969559 | 0.77 | KDM4E (0.62) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL8968935 | 0.74 | HTR6 (0.45) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL8969750 | 0.71 | MAOA (0.37) | LMNATSHRSMN1; SMN2MAOAACHE | |
| SCHEMBL8969191 | 0.70 | KDM4E (0.44) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL8969330 | 0.69 | KDM4E (0.59) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL8968953 | 0.69 | KDM4E (0.63) | ALDH1A1GAAHPGDKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |