Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.54 |
| ▸ | RAB9A | P51151 | 11/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 11/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | HPGD | P15428 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376024 | 0.82 | SMN1; SMN2 (0.48) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL714009 | 0.79 | ALOX5 (0.53) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL27713231 | 0.78 | ALOX5 (0.51) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL5919725 | 0.75 | MET (0.44) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL29531707 | 0.74 | NPC1 (0.69) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL824375 | 0.74 | NPC1 (0.69) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL760587 | 0.73 | NPC1 (0.68) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL13281919 | 0.73 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL20943719 | 0.72 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL28373720 | 0.72 | RAB9A (0.61) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519016-A | Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent | UBE INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |