SCHEMBL8970284

SCHEMBL8970284

CCCCO[C@H]1CCC[C@]1(Cl)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PPP5C P53041 1/20 0.34
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
TSHR P16473 1/20 0.32
DPP4 P27487 1/20 0.31
AKT1 P31749 3/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15217756 0.72 GRM2 (0.37) MEN1KMT2APPP5CLMNAHTT
SCHEMBL28734644 0.69 MEN1 (0.37) MEN1KMT2ALMNAHTTTSHR
SCHEMBL12329169 0.69 ARG1 (0.43) MEN1KMT2APPP5CLMNATSHR
SCHEMBL16391357 0.67 LMNA (0.34) MEN1KMT2APPP5CLMNAHTT
Hydrochloric Acid SCHEMBL3006667 0.66 ARG1 (0.38) MEN1KMT2APPP5CLMNATSHR
Bicarbonate SCHEMBL6206881 0.65 NAAA (0.50) PPP5CHTTALDH1A1
SCHEMBL10705341 0.64 SMN1; SMN2 (0.31)
SCHEMBL7702496 0.64 EPHX2 (0.39) MEN1KMT2APPP5CTSHRALDH1A1
SCHEMBL29412651 0.64 ARG1 (0.31)
SCHEMBL10699445 0.64 MEN1 (0.46) MEN1KMT2AHTTTSHRDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376294-B1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI LTD (JP) 1996-03-13 EP disclosed
US-5370821-A Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5269965-A Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES (JP) 1993-12-14 US disclosed
EP-0376294-A1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1990-07-04 EP disclosed