Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 11/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968355 | 0.89 | NOS3 (0.42) | NOS3NOS1NOS2ACHEALDH1A1 | |
| SCHEMBL9379110 | 0.84 | ACHE (0.39) | NOS3NOS1NOS2ACHEALDH1A1 | |
| SCHEMBL8969626 | 0.76 | NOS3 (0.42) | NOS3NOS1NOS2ACHEKLK7 | |
| SCHEMBL8968393 | 0.68 | ACHE (0.70) | ACHEALDH1A1GAAHTTHRH3 | |
| SCHEMBL9382126 | 0.68 | ACHE (0.34) | ACHEKLK7 | |
| SCHEMBL9381904 | 0.68 | ACHE (0.51) | ACHEALDH1A1HTTKDM4EHPGD | |
| SCHEMBL9380132 | 0.68 | ACHE (0.39) | NOS3NOS1NOS2ACHEALDH1A1 | |
| SCHEMBL9380948 | 0.68 | ACHE (0.39) | ACHEHTTHPGDKLK7 | |
| SCHEMBL9381591 | 0.68 | ACHE (0.39) | ACHEKLK7 | |
| SCHEMBL9382150 | 0.68 | ACHE (0.51) | ACHEKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |