Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 8/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970334 | 0.76 | NOS3 (0.42) | NOS3NOS1NOS2ACHEKLK7 | |
| SCHEMBL8968355 | 0.73 | NOS3 (0.42) | NOS3NOS1NOS2ACHEKDM1A | |
| SCHEMBL8968954 | 0.68 | ACHE (0.70) | ACHENPC1TSHRCASP3RAB9A | |
| SCHEMBL9385531 | 0.68 | ACHE (0.39) | ACHEKLK7SMN1; SMN2 | |
| SCHEMBL9380688 | 0.68 | ACHE (0.51) | ACHEKLK7TSHRSMN1; SMN2 | |
| SCHEMBL9381689 | 0.67 | ACHE (0.48) | NOS3NOS1NOS2ACHE | |
| SCHEMBL8968461 | 0.66 | ACHE (0.68) | ACHENPC1TSHRCASP3RAB9A | |
| SCHEMBL9380862 | 0.63 | ACHE (0.47) | NOS1ACHEKLK7SMN1; SMN2 | |
| SCHEMBL9380285 | 0.63 | ACHE (0.47) | NOS3NOS1NOS2ACHE | |
| SCHEMBL9382047 | 0.62 | ACHE (0.36) | ACHEKLK7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |