Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969661 | 0.85 | BCHE (0.34) | BCHEACHE | |
| SCHEMBL8969460 | 0.84 | ACHE (0.42) | MPOBCHEACHELRRK2 | |
| SCHEMBL8968555 | 0.84 | MPO (0.36) | MPOACHE | |
| SCHEMBL8969437 | 0.79 | BCHE (0.35) | BCHEACHE | |
| SCHEMBL8969894 | 0.77 | KDM4E (0.38) | BCHEACHE | |
| SCHEMBL8968356 | 0.77 | — | — | |
| SCHEMBL8969797 | 0.76 | LRRK2 (0.39) | MPOACHELRRK2 | |
| SCHEMBL8968811 | 0.76 | LRRK2 (0.38) | LRRK2CYP11B2CYP11B1 | |
| SCHEMBL8968456 | 0.75 | ACHE (0.37) | ACHE | |
| SCHEMBL8969453 | 0.74 | ACHE (0.45) | BCHEACHECYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |