Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 16/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | LCT | P09848 | 2/20 | 0.32 |
| ▸ | UGCG | Q16739 | 2/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12760016 | 0.87 | NAAA (0.33) | NAAAESR1 | |
| SCHEMBL8970743 | 0.86 | GABRA1 (0.32) | NAAA | |
| SCHEMBL8969516 | 0.86 | SLC6A2 (0.36) | NAAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8972116 | 0.84 | FGFR2 (0.32) | NAAA | |
| SCHEMBL8969132 | 0.84 | NAAA (0.35) | NAAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12760014 | 0.84 | NAAA (0.34) | NAAAESR1 | |
| SCHEMBL8970851 | 0.84 | NAAA (0.41) | NAAACTSKGBA1LCTUGCG | |
| SCHEMBL8945177 | 0.84 | FPR2 (0.33) | NAAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8971187 | 0.83 | NAAA (0.41) | NAAACTSKGBA1LCTUGCG | |
| SCHEMBL8970518 | 0.83 | NAAA (0.34) | NAAASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |