Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970664 | 0.88 | HTR4 (0.67) | MEN1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL6244982 | 0.87 | HTR4 (0.66) | MEN1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7354179 | 0.79 | HTR4 (0.78) | MEN1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8970723 | 0.78 | HTR4 (0.55) | MEN1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8971469 | 0.72 | MEN1 (0.69) | MEN1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8971283 | 0.72 | HTR4 (0.49) | MEN1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8971342 | 0.72 | HTR4 (0.63) | MEN1ALDH1A1CYP2D6KMT2AHTR4 | |
| Hydrochloric Acid SCHEMBL8970748 | 0.71 | HTR4 (0.62) | MEN1ALDH1A1CYP2D6KMT2AHTR4 | |
| SCHEMBL548884 | 0.71 | HTR4 (1.00) | MEN1ALDH1A1CYP3A4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL8971374 | 0.71 | DRD2 (0.52) | MEN1ALDH1A1CYP2D6KMT2AHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |