Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743092 | 0.85 | GPR35 (0.50) | ALDH1A1HPGDTDP1GPR35MAPK1 | |
| SCHEMBL8065807 | 0.85 | GPR35 (0.50) | ALDH1A1HPGDTDP1GPR35MAPK1 | |
| SCHEMBL731102 | 0.82 | MCOLN3 (0.60) | MCOLN3CRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL8970608 | 0.82 | VCAM1 (0.46) | MCOLN3CRHBPCRHR2CCR2ALDH1A1 | |
| SCHEMBL8970954 | 0.81 | CCR2 (0.43) | MCOLN3CRHBPCRHR2CCR2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28777156 | 0.81 | MCOLN3 (0.59) | MCOLN3CRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL9568275 | 0.81 | MCOLN3 (0.59) | MCOLN3CRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL9568274 | 0.81 | MCOLN3 (0.59) | MCOLN3CRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL4479896 | 0.75 | NSD2 (0.53) | MCOLN3CRHBPCRHR2ALDH1A1HPGD | |
| SCHEMBL4479899 | 0.75 | NSD2 (0.53) | MCOLN3CRHBPCRHR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700287-A1 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027584-A2 | ARYLATING MEDICAMENTS | RADOPATH LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |