SCHEMBL8970946

SCHEMBL8970946

CC(CO)C(=O)c1ccc(C(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP5 P45974 1/20 0.50
CYP2C9 P11712 2/20 0.47
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 5/20 0.43
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
LMNA P02545 2/20 0.43
POLB P06746 2/20 0.43
RAB9A P51151 4/20 0.42
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
HPGD P15428 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29018406 0.84 CES2 (0.46) HTTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL18101846 0.84 CES2 (0.46) HTTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL13672815 0.82 CHRM2 (0.56) HTTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL29085758 0.82 LMNA (0.51) HTTALDH1A1LMNAPOLBRAB9A
SCHEMBL18101799 0.82 LMNA (0.51) HTTALDH1A1LMNAPOLBRAB9A
SCHEMBL29018405 0.80 CES2 (0.46) HTTALDH1A1MEN1KMT2ALMNA
SCHEMBL11812546 0.80 CES2 (0.46) SMN1; SMN2ALDH1A1LMNAPOLBRAB9A
SCHEMBL9850647 0.79 EGFR (0.50) USP5CYP2C9HTTSMN1; SMN2ALDH1A1
SCHEMBL2736656 0.79 L3MBTL1 (0.54) HTTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL2736655 0.79 L3MBTL1 (0.54) HTTSMN1; SMN2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61181809-A None JP disclosed
EP-3827955-A1 IMPROVED ANTIMONY-FREE RADIATION CURABLE COMPOSITIONS FOR ADDITIVE FABRICATION, AND APPLICATIONS THEREOF IN INVESTMENT CASTING PROCESSES DSM IP Assets B.V. (NL) 2021-06-02 EP disclosed
US-20190284430-A1 LED CURABLE COATINGS FOR FLOORING COMPRISING DIAMOND PARTICLES AND METHODS FOR MAKING THE SAME AFI LICENSING LLC 2019-09-19 US disclosed
CN-102964515-B Resin for interlayer insulating film and protective film, and photosensitive resin composition EVERLIGHT CHEMICAL INDUSTRIAL CORP. (CN) 2015-08-19 CN disclosed
US-20140326988-A1 SUBSTRATE FOR OPTICS AND LIGHT EMITTING DEVICE ASAHI KASEI E-MATERIALS CORPORATION (JP) 2014-11-06 US disclosed
US-5506051-A LAMINATE HAVING RADIATION-CURED URETHANE ACRYLATE OR POLYETHER ACRYLATE OLIGOMERS; ELONGATION, TOUGHNESS NICOLECTRONIX LTD. LABORATORIES (IL) 1996-04-09 US disclosed
JP-S61181809-A PHOTOCURABLE COMPOSITION IDEMITSU PETROCHEM CO LTD 1986-08-14 JP disclosed