Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | USP5 | P45974 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10353456 | 0.89 | EGFR (0.58) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9859087 | 0.86 | EGFR (0.50) | EGFRHPGDHDAC3HDAC4HDAC1 | |
| SCHEMBL9850638 | 0.84 | CHRM2 (0.51) | EGFRHPGDHDAC3HDAC4HDAC1 | |
| SCHEMBL10384775 | 0.82 | EGFR (0.50) | EGFRHPGDHDAC3HDAC4HDAC1 | |
| SCHEMBL9683311 | 0.81 | NPC1 (0.64) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6726553 | 0.81 | NPC1 (0.64) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL9324495 | 0.80 | MAPT (0.67) | EGFRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8970946 | 0.79 | USP5 (0.50) | HPGDUSP5HDAC3HDAC4HDAC1 | |
| SCHEMBL7590256 | 0.79 | ALDH1A1 (0.56) | EGFRHPGDHDAC3HDAC4HDAC1 | |
| SCHEMBL11497403 | 0.79 | HTT (0.64) | EGFRHPGDHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423524-A2 | Propiophenone derivatives and their preparation and pharmaceutical use | MARUHO Co., Ltd. (JP) | 1991-04-24 | — | — | EP | disclosed |