SCHEMBL1171368

SCHEMBL1171368

CN(CCC(Oc1ccccc1C(F)(F)F)c1ccccc1)CC(=O)O

nearest known ligand 0.68

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 20/20 0.68
ALDH1A1 P00352 1/20 0.59
CYP2D6 P10635 1/20 0.59
MAPT P10636 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
SLC6A5 Q9Y345 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8971145 0.83 SLC6A4 (0.51) SLC6A9
Fumaric Acid SCHEMBL9445703 0.82 SLC6A9 (0.47) SLC6A9
SCHEMBL15127607 0.81 SLC6A9 (1.00) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL1171367 0.81 SLC6A9 (1.00) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL8971666 0.81 SLC6A4 (0.49) SLC6A9ALDH1A1CYP2D6CYP2C9CYP2C19
SCHEMBL6259387 0.80 SLC6A9 (0.72) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL8971243 0.79 SLC6A9 (0.44) SLC6A9
SCHEMBL6826726 0.78 SLC6A9 (0.55) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL6567420 0.78 SLC6A9 (0.93) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9
SCHEMBL6254425 0.78 SLC6A9 (0.85) SLC6A9ALDH1A1CYP2D6MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020219975-A1 COMPOSITIONS FOR IMPROVING BRAIN HEALTH AND MEMORY CYTOSOLVE, INC. (US) 2020-10-29 WO claimed
WO-2006034196-A1 COMPOSITIONS FOR ENHANCING MEMORY AND METHODS THEREFOR LIFELIKE BIOMATIC INC. (US) 2006-03-30 WO claimed
US-20060063707-A1 Compositions for enhancing memory and methods therefor LIFELIKE BIOMATIC, INC. (US) 2006-03-23 US claimed
US-20220117284-A1 Compositions for Improving Low Testosterone Levels CYTOSOLVE, INC. 2022-04-21 US disclosed
WO-2020219975-A1 COMPOSITIONS FOR IMPROVING BRAIN HEALTH AND MEMORY CYTOSOLVE, INC. (US) 2020-10-29 WO disclosed
EP-2288345-B1 PSYCHO-PHARMACEUTICALS UNIV DUBLIN (IE) 2015-06-10 EP disclosed
WO-2011067225-A1 COMPOSITIONS TARGETING CB1 RECEPTOR FOR CONTROLLING FOOD INTAKE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2011-06-09 WO disclosed
EP-2288345-A1 PSYCHO-PHARMACEUTICALS University College Dublin National University Of Ireland, Dublin (IE) 2011-03-02 EP disclosed
US-20110034565-A1 PSYCHO-PHARMACEUTICALS UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) 2011-02-10 US disclosed
WO-2009128058-A1 PSYCHO-PHARMACEUTICALS UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN et al (IE) 2009-10-22 WO disclosed
WO-2006034196-A1 COMPOSITIONS FOR ENHANCING MEMORY AND METHODS THEREFOR LIFELIKE BIOMATIC INC. (US) 2006-03-30 WO disclosed
US-20060063707-A1 Compositions for enhancing memory and methods therefor LIFELIKE BIOMATIC, INC. (US) 2006-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063707-A1 Compositions for enhancing memory and methods therefor GRIN1, GRIN3A, GRIN2A SLC6A9 2144/4885ALDH1A1 4321/4885CYP2D6 4863/4885
US-20110034565-A1 PSYCHO-PHARMACEUTICALS PNMT, HTR3C, HTR5A SLC6A9 3575/4885ALDH1A1 2279/4885CYP2D6 234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.