Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971117 | 0.93 | AGER (0.47) | AGERHTTALDH1A1POLBCYP3A4 | |
| SCHEMBL10718171 | 0.84 | AGER (0.48) | AGERHTTALDH1A1POLBMEN1 | |
| SCHEMBL8971443 | 0.83 | PGK1 (0.40) | HTTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8971710 | 0.80 | HTR4 (0.48) | ALDH1A1CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL8971982 | 0.80 | SMN1; SMN2 (0.41) | AGERALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL5757320 | 0.80 | HTT (0.50) | AGERHTTALDH1A1POLBMEN1 | |
| SCHEMBL8970918 | 0.79 | MTNR1B (0.43) | AGERALDH1A1POLBCYP3A4MEN1 | |
| SCHEMBL8970849 | 0.79 | KDM4E (0.50) | AGERALDH1A1POLBCYP3A4MEN1 | |
| SCHEMBL8971265 | 0.78 | SMN1; SMN2 (0.42) | AGERALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL8971536 | 0.77 | MGAT2 (0.44) | ALDH1A1MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |