SCHEMBL8971499

SCHEMBL8971499

CC(=O)CCCN1CCC(NC(N)=O)CC1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 2/20 0.46
ADRA1D P25100 1/20 0.46
ADRA1A P35348 1/20 0.46
ADRA1B P35368 1/20 0.46
LTA4H P09960 2/20 0.43
EPHX1 P07099 2/20 0.42
EPHX2 P34913 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
POLB P06746 1/20 0.40
HTT P42858 1/20 0.40
CARM1 Q86X55 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
SMYD3 Q9H7B4 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CHRM1 P11229 2/20 0.38
KDM1A O60341 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11960652 0.84 EPHX1 (0.57) LTA4HEPHX1EPHX2SMN1; SMN2L3MBTL1
SCHEMBL27669922 0.81 GNAI3 (0.54) EPHX1EPHX2
SCHEMBL12992387 0.79 SMN1; SMN2 (0.59) PAOXSMN1; SMN2POLBL3MBTL1
SCHEMBL4653709 0.78 PAOX (0.53) PAOXADRA1ASMN1; SMN2POLBHTT
SCHEMBL27570291 0.78 LTA4H (0.48) LTA4HEPHX1EPHX2SMN1; SMN2CARM1
SCHEMBL8971106 0.77 PAOX (0.45) PAOXADRA1DADRA1AADRA1BEPHX1
SCHEMBL12022073 0.76 PAOX (0.55) PAOXADRA1ASMN1; SMN2POLBHTT
SCHEMBL27348781 0.76 SMN1; SMN2 (0.58) LTA4HEPHX1EPHX2SMN1; SMN2L3MBTL1
SCHEMBL8971713 0.76 KMT2A (0.55) PAOXADRA1APOLBHTTCARM1
SCHEMBL27688983 0.76 PARP1 (0.49) LTA4HEPHX1EPHX2SMN1; SMN2CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700383-A1 NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS SYNTEX (U.S.A.) INC. (US) 1996-03-13 EP disclosed