Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 6/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942938 | 0.81 | GNAI3 (0.45) | DRD3DRD2HTR2AEPHX1EPHX2 | |
| SCHEMBL8971627 | 0.77 | HTR4 (0.44) | PAOXADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL12678541 | 0.77 | DRD2 (0.42) | DRD3DRD2HTR2AEPHX1EPHX2 | |
| SCHEMBL11537811 | 0.77 | ADRA1A (0.68) | ADRA1AADRA1DADRA1BDRD3DRD2 | |
| SCHEMBL8971499 | 0.77 | PAOX (0.46) | PAOXKDM1AADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL11534746 | 0.76 | MEN1 (0.67) | ADRA1ADRD3DRD2HTR2AMEN1 | |
| SCHEMBL7357324 | 0.76 | HTR2A (0.36) | KDM1ADRD3DRD2HTR2AHTR1A | |
| SCHEMBL12022073 | 0.75 | PAOX (0.55) | PAOXADRA1ADRD3POLBHTT | |
| SCHEMBL8971713 | 0.75 | KMT2A (0.55) | PAOXADRA1ACA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL8604286 | 0.74 | ADRA1D (0.62) | KDM1AADRA1AADRA1DADRA1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |