Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.50 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20397370 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TP53EPHX2PPARGASAH2 | |
| SCHEMBL29536611 | 0.91 | PPARG (0.58) | ALDH1A1TP53EPHX2PPARGASAH2 | |
| SCHEMBL8971889 | 0.86 | DGKA (0.52) | ALDH1A1PPARGGPR132TDP1 | |
| SCHEMBL8971883 | 0.86 | DGKA (0.52) | ALDH1A1PPARGGPR132TDP1 | |
| SCHEMBL18907111 | 0.84 | EPHX2 (0.58) | ALDH1A1TP53EPHX2ASAH2THRB | |
| SCHEMBL18398889 | 0.82 | PPARG (0.66) | PPARGGPR132KMT2ATDP1 | |
| SCHEMBL31359284 | 0.81 | PPARG (0.73) | PPARGGPR132MEN1KMT2AALOX5 | |
| SCHEMBL10695303 | 0.81 | TRPA1 (0.56) | ALDH1A1PPARGGPR132 | |
| SCHEMBL10695309 | 0.81 | TRPA1 (0.56) | ALDH1A1PPARGGPR132 | |
| SCHEMBL22625597 | 0.80 | FFAR1 (0.61) | EPHX2ALOX5OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435293-B1 | Methods of producing optically active hydroxyesters | NITTO DENKO CORP (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5272069-A | Method of producing optically active hydroxyesters | NITTO DENKO CO. LTD. (JP) | 1993-12-21 | — | — | US | disclosed |
| EP-0435293-A2 | Methods of producing optically active hydroxyesters | Nitto Denko Co. Ltd. (JP) | 1991-07-03 | — | — | EP | disclosed |