Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971431 | 0.91 | BIRC2 (0.41) | BIRC2CTSSPSEN1PSEN2APH1B | |
| SCHEMBL8972617 | 0.90 | BIRC2 (0.40) | BIRC2CTSSPSEN1PSEN2APH1B | |
| SCHEMBL8972090 | 0.88 | BIRC2 (0.43) | BIRC2CTSSPSEN1PSEN2APH1B | |
| SCHEMBL8972038 | 0.88 | ALDH1A1 (0.44) | BIRC2CTSSRENCTSKCTSD | |
| SCHEMBL8972096 | 0.84 | CTSK (0.40) | BIRC2CTSSPSMB5RENCTSK | |
| SCHEMBL8972083 | 0.80 | DPP7 (0.42) | BIRC2RENCTSK | |
| SCHEMBL8972325 | 0.77 | CTSK (0.63) | CTSSPSMB5CTSKCTSL | |
| SCHEMBL8971543 | 0.76 | ALDH1A1 (0.43) | BIRC2CTSSRENCTSKCTSD | |
| SCHEMBL8972538 | 0.75 | ALDH1A1 (0.42) | BIRC2CTSSRENCTSKCTSD | |
| SCHEMBL8972471 | 0.75 | ALDH1A1 (0.42) | BIRC2CTSSRENCTSKCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543310-B1 | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5395824-A | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LIMITED (JP) | 1995-03-07 | — | — | US | disclosed |