Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | THRA | P10827 | 7/20 | 0.62 |
| ▸ | THRB | P10828 | 7/20 | 0.62 |
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28013341 | 0.88 | THRA (0.64) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL83484 | 0.87 | THRA (0.68) | L3MBTL1HPGDTHRATHRBHSD17B3 | |
| SCHEMBL13131234 | 0.86 | SMN1; SMN2 (0.61) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL28013318 | 0.84 | L3MBTL1 (0.72) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL15960542 | 0.84 | THRA (0.79) | THRATHRBHAO1 | |
| Butylbenzyl SCHEMBL8119801 | 0.83 | L3MBTL1 (0.69) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL27463271 | 0.82 | DPP4 (0.81) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL30089476 | 0.82 | THRA (0.70) | L3MBTL1HPGDTHRATHRBHSD17B3 | |
| SCHEMBL28908404 | 0.81 | THRA (0.79) | L3MBTL1THRATHRBHSD17B3HAO1 | |
| SCHEMBL8971789 | 0.81 | THRA (0.60) | L3MBTL1THRATHRBHSD17B3HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943646-B2 | Benzamidine derivative, process for the preparation thereof and pharmaceutical composition comprising same | DONG WHA PHARMACEUTICAL CO., LTD. (KR) | 2011-05-17 | — | — | US | disclosed |
| US-20090054642-A1 | NOVEL BENZAMIDINE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | DONGWHA PHARMACEUTICAL IND. CO., LTD. (KR) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054642-A1 | NOVEL BENZAMIDINE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SOST, BMP4, BST2 | NPC1 2456/4885RAB9A 453/4885CASP3 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.