Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17002620 | 0.74 | MTNR1A (0.53) | MTNR1ASCN1ASCN2ASCN3AMEN1 | |
| SCHEMBL7204577 | 0.72 | MTNR1A (0.51) | MTNR1ASCN1ASCN2ASCN3A | |
| SCHEMBL7203114 | 0.72 | MTNR1A (0.47) | MTNR1ASCN1ASCN2ASCN3A | |
| SCHEMBL9261138 | 0.70 | DRD2 (0.51) | DRD4MEN1KMT2A | |
| SCHEMBL6555327 | 0.69 | MTNR1A (0.57) | MTNR1ASCN1ASCN2ASCN3A | |
| SCHEMBL7198607 | 0.69 | MTNR1A (0.53) | MTNR1ASCN1ASCN2ASCN3AALDH1A1 | |
| SCHEMBL7203987 | 0.69 | MTNR1A (0.53) | MTNR1ASCN1ASCN2ASCN3A | |
| SCHEMBL30906151 | 0.65 | LMNA (0.40) | SCN1ASCN2ASCN3ACYP2D6ALDH1A1 | |
| SCHEMBL6437548 | 0.65 | AHR (0.46) | MTNR1ALMNA | |
| SCHEMBL7198985 | 0.62 | MTNR1A (0.73) | MTNR1ASCN1ASCN2ASCN3AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310524-A | TCA Composition and method for rapid onset antidepressant therapy | RICHARDSON-MERRELL, INC. (US) | 1982-01-12 | — | — | US | claimed |
| CN-109824646-B | Method for synthesizing optically pure 2-hydroxymethyl-1, 4-benzodioxan and derivative thereof | 陕西师范大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-109824646-A | A kind of method of the pure 2- methylol -1,4- benzodioxane of synthesizing optical and its derivative | 陕西师范大学 | 2019-05-31 | — | — | CN | disclosed |
| EP-0700285-A1 | A DRUG DELIVERY COMPOSITION FOR ALPHA-ADRENO RECEPTOR BLOCKING AGENTS | SYNTHELABO (FR) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027582-A1 | A DRUG DELIVERY COMPOSITION FOR ALPHA-ADRENO RECEPTOR BLOCKING AGENTS | DANBIOSYST UK LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |
| US-5338550-A | Stereoisomer therapy | ALZA CORPORATION (US) | 1994-08-16 | — | — | US | disclosed |
| US-5204116-A | Dosage form providing immediate therapy followed by prolonged therapy | ALZA CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| US-4310524-A | TCA Composition and method for rapid onset antidepressant therapy | RICHARDSON-MERRELL, INC. (US) | 1982-01-12 | — | — | US | disclosed |