Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971988 | 0.90 | PLA2G2D (0.32) | S1PR1PTPN11PLA2G2DFPR2 | |
| SCHEMBL8972224 | 0.90 | PLA2G2D (0.32) | S1PR1PTPN11PLA2G2DFPR2 | |
| SCHEMBL8971880 | 0.89 | S1PR1 (0.33) | PPARDS1PR1S1PR3PTPN11THRA | |
| SCHEMBL8970757 | 0.85 | PTPN11 (0.34) | PPARDS1PR1S1PR3RARBFFAR1 | |
| SCHEMBL8971848 | 0.84 | GRM2 (0.35) | PPARDGRM2S1PR1S1PR3FFAR1 | |
| SCHEMBL8971890 | 0.84 | GRM2 (0.34) | GRM2S1PR1S1PR3 | |
| SCHEMBL8971819 | 0.82 | RARB (0.37) | PPARDS1PR1S1PR3RARBPTPN11 | |
| SCHEMBL8953724 | 0.82 | FPR2 (0.36) | PPARDRARBPTPN11THRATHRB | |
| SCHEMBL8953332 | 0.82 | FPR2 (0.36) | PPARDRARBPTPN11THRATHRB | |
| SCHEMBL8953544 | 0.82 | FPR2 (0.36) | PPARDRARBPTPN11THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |