Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971939 | 0.93 | SLC6A2 (0.34) | GRM2APPCYP2C9 | |
| SCHEMBL15340235 | 0.86 | — | — | |
| SCHEMBL8972405 | 0.85 | FPR2 (0.30) | — | |
| SCHEMBL8972128 | 0.84 | PPARD (0.34) | GRM2S1PR1S1PR3 | |
| SCHEMBL8971724 | 0.82 | GRM2 (0.33) | GRM2 | |
| SCHEMBL8943442 | 0.81 | FPR2 (0.35) | — | |
| SCHEMBL8970464 | 0.80 | FFAR4 (0.33) | HMOX1S1PR1S1PR3 | |
| SCHEMBL8971848 | 0.80 | GRM2 (0.35) | GRM2S1PR1S1PR3 | |
| SCHEMBL8971604 | 0.80 | GRM2 (0.38) | GRM2APPCYP2C9 | |
| SCHEMBL8944006 | 0.80 | FPR2 (0.35) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |