Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431626 | 0.98 | — | — | |
| SCHEMBL10759 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL29424070 | 0.95 | MAPK1 (0.46) | MAPK1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL2446692 | 0.95 | MAPK1 (0.46) | MAPK1ALDH1A1KDM4EGLAGAA | |
| Formic Acid SCHEMBL29774382 | 0.86 | KMT2A (0.42) | MAPK1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL28135793 | 0.82 | QPCT (0.49) | MAPK1ALDH1A1KDM4EGLAGAA | |
| Trifluoroacetic Acid SCHEMBL29858985 | 0.80 | L3MBTL1 (0.40) | MAPK1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL8653543 | 0.80 | TLR8 (0.35) | MAPK1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL1809684 | 0.78 | KDM4E (0.33) | MAPK1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL28135193 | 0.78 | DAO (0.42) | ALDH1A1KDM4EGLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506238-A | HYPOTENSIVE AGENT | EISAI CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |