Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL29858985

O=C(O)C(F)(F)F.c1cnc2[nH]cnc2c1

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.40
UBE2N P61088 1/20 0.39
NAMPT P43490 1/20 0.36
APAF1 O14727 1/20 0.36
PABPC1 P11940 1/20 0.36
CASP6 P55212 1/20 0.36
CASP8 Q14790 1/20 0.36
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 3/20 0.36
ALOX15 P16050 2/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.36
BLM P54132 1/20 0.36
AGER Q15109 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PLOD2 O00469 1/20 0.36
PLOD3 O60568 1/20 0.36
PLOD1 Q02809 1/20 0.36
CAMKK2 Q96RR4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10759 0.82
SCHEMBL29431626 0.82
SCHEMBL2446692 0.80 MAPK1 (0.46) ALDH1A1KDM4EALOX15MAPTMAPK1
Ammonia Solution, Strong SCHEMBL8971987 0.80 MAPK1 (0.46) ALDH1A1KDM4EALOX15MAPTMAPK1
Hydrochloric Acid SCHEMBL29424070 0.80 MAPK1 (0.46) ALDH1A1KDM4EALOX15MAPTMAPK1
Trifluoroacetic Acid SCHEMBL30083057 0.80 L3MBTL1 (0.44) L3MBTL1UBE2NALDH1A1KDM4EALOX15
Formic Acid SCHEMBL29774382 0.80 KMT2A (0.42) L3MBTL1NAMPTALDH1A1KDM4EALOX15
Trifluoroacetic Acid SCHEMBL22397327 0.79 L3MBTL1 (0.45) L3MBTL1UBE2NALDH1A1KDM4EALOX15
Trifluoroacetic Acid SCHEMBL34473163 0.77 L3MBTL1 (0.40) L3MBTL1UBE2NAPAF1PABPC1CASP6
Benzimidazole SCHEMBL2073386 0.77 RAB9A (0.50) NAMPTCASP6ALDH1A1KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107922396-B Colony stimulating factor-1 receptor (CSF-1R) inhibitors 建新公司 2022-08-05 CN disclosed