Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 10/20 | 0.33 |
| ▸ | AKT1 | P31749 | 5/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12396466 | 0.76 | HTR2A (0.38) | HTR2AHTR2CSLC6A4GRIA2AKT1 | |
| SCHEMBL17475922 | 0.73 | IDH1 (0.41) | IDH1 | |
| SCHEMBL12370921 | 0.72 | GRIA2 (0.35) | HTR2AHTR2CSLC6A4GRIA2IDH1 | |
| SCHEMBL4265285 | 0.68 | BRPF1 (0.41) | — | |
| SCHEMBL8653546 | 0.68 | GRIA2 (0.38) | GRIA2 | |
| SCHEMBL10153799 | 0.67 | HTR2C (0.41) | HTR2AHTR2CSLC6A4GRIA2 | |
| Hydrochloric Acid SCHEMBL7050100 | 0.66 | HTR2C (0.40) | HTR2AHTR2CSLC6A4GRIA2 | |
| SCHEMBL517896 | 0.65 | HTR2A (0.42) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL19976715 | 0.65 | EPHX2 (0.34) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL7407636 | 0.64 | LMNA (0.39) | HTR2CAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506238-A | HYPOTENSIVE AGENT | EISAI CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |