Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.40 |
| ▸ | CCKBR | P32239 | 3/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572313 | 0.76 | SLC7A5 (0.40) | — | |
| SCHEMBL8972573 | 0.76 | ALDH1A1 (0.42) | ALDH1A1PLA2G2APLA2G5SIRT6SIRT1 | |
| SCHEMBL8972578 | 0.76 | ALDH1A1 (0.42) | ALDH1A1PLA2G2APLA2G5SIRT6SIRT1 | |
| SCHEMBL8972026 | 0.76 | CTSK (0.58) | CCKBR | |
| SCHEMBL8971858 | 0.75 | ALDH1A1 (0.50) | ALDH1A1 | |
| Acetylleucine SCHEMBL27864478 | 0.73 | ALDH1A1 (0.79) | ALDH1A1PLA2G2APLA2G5SIRT6SIRT1 | |
| SCHEMBL1981143 | 0.71 | CCKBR (0.59) | CCKBR | |
| SCHEMBL18796618 | 0.70 | FAAH (0.54) | PLA2G2APLA2G5 | |
| SCHEMBL18796619 | 0.70 | FAAH (0.54) | PLA2G2APLA2G5 | |
| SCHEMBL7299506 | 0.69 | PSEN1 (0.41) | ALDH1A1PLA2G2APLA2G5CCKBRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543310-B1 | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5395824-A | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LIMITED (JP) | 1995-03-07 | — | — | US | disclosed |