SCHEMBL8972258

SCHEMBL8972258

C=CC(=O)OOC(COCC)(OC(=O)OC(COCC)(OOC(=O)C=C)C(C)(C)c1ccc(C(C)C)cc1)C(C)(C)c1ccc(C(C)C)cc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
HIF1A Q16665 1/20 0.32
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9336308 0.90 CYP2D6 (0.33) CYP2D6CYP2C9HIF1ALMNAHTT
SCHEMBL7692315 0.87 CYP2C19 (0.33) CYP2C9HIF1A
SCHEMBL7690555 0.78 THRB (0.35) HIF1ASMN1; SMN2
SCHEMBL9862019 0.77 LMNA (0.37) CYP2D6CYP2C9HIF1ALMNAHTT
SCHEMBL10482043 0.77 THRB (0.35)
SCHEMBL3385457 0.76 CYP2D6 (0.36) CYP2D6CYP2C9HIF1A
SCHEMBL7683837 0.75 THRB (0.36)
SCHEMBL7685235 0.73 THRB (0.32)
SCHEMBL3385618 0.66 CYP2D6 (0.35) CYP2D6CYP2C9HIF1A
SCHEMBL3380731 0.66 CYP2D6 (0.33) CYP2D6CYP2C9HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
EP-0338544-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1996-07-31 EP disclosed
EP-0423767-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1996-03-06 EP disclosed
EP-0338303-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1995-11-15 EP disclosed
US-5438098-A Blend of polyarylene sulfie;, polycarbonater and/or acrylonitrile-butadiene-styrene resin, and epoxy group containing defin graft polymer as compatibilizer NIPPON PETROCHEMICALS CO., LTD. (JP) 1995-08-01 US disclosed
EP-0334296-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1995-06-07 EP disclosed
EP-0289933-B1 Graft polymerization precurser and method manufacturing the same NIPPON OILS & FATS CO LTD (JP) 1994-07-13 EP disclosed
EP-0279430-B1 The method of manufacturing a grafted resin composition NIPPON OILS & FATS CO LTD (JP) 1994-06-15 EP disclosed
US-5296538-A Polyarylene sulfide, polycarbonate, polyphenylene ether and graft copolymer for automobile parts and electronics NIPPON PETROCHEMICALS CO., LTD. (JP) 1994-03-22 US disclosed
US-5244973-A POLYAMIDE RESIN THERMOPLASTIC BLEND CONTAINING A MULTI-PHASE STRUCTURE THERMOPLASTIC RESIN COMPATIBILIZATION AGENT AND PROGESS FOR THE PRODUCTION THEREOF NIPPON PETROCHEMICALS CO., LTD. (JP) 1993-09-14 US disclosed
US-5157070-A Engineering blends having impact strength, heat resistance, moldability, dimensional stability NIPPON PETROCHEMICALS CO., LTD. (JP) 1992-10-20 US disclosed
EP-0506006-A2 Thermoplastic resin composition NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-09-30 EP disclosed
US-5036120-A Polyoxymethylene and/or polycarbonate, ethylene-glycidyl acrylate or methacrylate polymer, addition polymer with peroxy groups, graft polymerization NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-07-30 US disclosed
EP-0412572-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-02-13 EP disclosed
US-4987165-A MULTIPHASE COMPATIBILIZER FOR BLEND OF POLYSULFONE AND ACRYLONITRILE-BUTADIENE-STYRENE TERPOLYMER NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-01-22 US disclosed