Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862000 | 0.86 | GSTO1 (0.36) | LMNASMN1; SMN2CYP2C9TSHRMEN1 | |
| SCHEMBL8972258 | 0.77 | CYP2D6 (0.32) | LMNASMN1; SMN2HTTCYP2D6CYP2C9 | |
| SCHEMBL10498325 | 0.76 | ALDH1A1 (0.38) | SMN1; SMN2HIF1ATSHRHPGDKDM4E | |
| SCHEMBL9862091 | 0.73 | THRB (0.36) | SMN1; SMN2HIF1ATSHRHPGDALDH1A1 | |
| SCHEMBL3385457 | 0.71 | CYP2D6 (0.36) | CYP2D6CYP2C9HIF1AKDM4E | |
| SCHEMBL10349877 | 0.71 | THRB (0.36) | LMNASMN1; SMN2HTTCYP2D6CYP2C9 | |
| SCHEMBL9851458 | 0.71 | LMNA (0.39) | LMNASMN1; SMN2HTTCYP2D6CYP2C9 | |
| SCHEMBL9851460 | 0.70 | LMNA (0.37) | LMNASMN1; SMN2HTTCYP2D6CYP2C9 | |
| SCHEMBL9336308 | 0.70 | CYP2D6 (0.33) | LMNASMN1; SMN2HTTCYP2D6CYP2C9 | |
| SCHEMBL9847989 | 0.69 | LMNA (0.38) | LMNASMN1; SMN2HTTCYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423767-A2 | Thermoplastic resin composition and method for preparing the same | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-04-24 | — | — | EP | disclosed |