SCHEMBL8973056

SCHEMBL8973056

C[SiH](C)C[Si](C)(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
NR1H2 P55055 2/20 0.33
NR1H3 Q13133 2/20 0.33
MGAM O43451 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14866586 0.81 ESR1 (0.37) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL6833296 0.75 MAPT (0.44) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL9217667 0.74 MAPT (0.47) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL9226507 0.72 MAPT (0.45) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL25284860 0.70 MAPT (0.44) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL18084487 0.70 MGAM (0.44) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL9712158 0.70 MAPT (0.48) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL852172 0.70 MAPT (0.44) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL3614652 0.70 MAPT (0.48) MAPTESR1ESR2NR1H2NR1H3
SCHEMBL10523358 0.70 MAPT (0.44) MAPTESR1ESR2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545409-B1 Liquid crystals with end groups containing more than one silane group CONSORTIUM ELEKTROCHEM IND (DE) 1996-03-06 EP disclosed
US-5399290-A Liquid crystals with (polysila) alkyl wing groups CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1995-03-21 US disclosed
EP-0545409-A1 Liquid crystals with end groups containing more than one silane group Consortium für elektrochemische Industrie GmbH (DE) 1993-06-09 EP disclosed