Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305346 | 0.90 | HPGD (0.41) | NPC1RAB9AHPGDSMN1; SMN2MBOAT4 | |
| SCHEMBL9304882 | 0.87 | RAB9A (0.42) | NPC1RAB9AHPGDSMN1; SMN2MBOAT4 | |
| SCHEMBL10893433 | 0.87 | SIRT5 (0.41) | NPC1RAB9AHPGDSMN1; SMN2MBOAT4 | |
| SCHEMBL9307864 | 0.87 | NPC1 (0.52) | NPC1RAB9AHPGDSMN1; SMN2MBOAT4 | |
| SCHEMBL10892216 | 0.85 | HPGD (0.44) | NPC1RAB9AHPGDSMN1; SMN2MBOAT4 | |
| SCHEMBL9306165 | 0.85 | TP53 (0.44) | NPC1RAB9AHPGDSMN1; SMN2MBOAT4 | |
| SCHEMBL8972664 | 0.85 | SMN1; SMN2 (0.47) | NPC1RAB9AHPGDSMN1; SMN2POLB | |
| SCHEMBL8972438 | 0.85 | LMNA (0.51) | HPGDSMN1; SMN2MBOAT4CYP1A2CYP2C19 | |
| SCHEMBL9305598 | 0.82 | ALDH1A1 (0.42) | NPC1RAB9AELANEKMT2AMEN1 | |
| SCHEMBL9306890 | 0.82 | CETP (0.42) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5549847-A | STIRRING A FILTER CAKE OF CORROSION INHIBITOR WITH DISPERSANT AND THICKENER; STORAGE STABILITY | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |