Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973411 | 0.84 | PKM (0.52) | ALDH1A1HSD17B10TSHRSMN1; SMN2LMNA | |
| SCHEMBL10594253 | 0.84 | MMP2 (0.64) | ALDH1A1HSD17B10SMN1; SMN2MMP2PKM | |
| SCHEMBL8973126 | 0.83 | MEN1 (0.50) | ALDH1A1HSD17B10SMN1; SMN2MMP2KDM2B | |
| SCHEMBL8973637 | 0.79 | MMP2 (0.46) | ALDH1A1HSD17B10MMP2PKMTDP1 | |
| SCHEMBL8973357 | 0.79 | MEN1 (0.51) | ALDH1A1HSD17B10MMP2KDM2BTDP1 | |
| SCHEMBL8800496 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2PKMHTTMEN1 | |
| SCHEMBL8973311 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HSD17B10SMN1; SMN2LMNAPKM | |
| SCHEMBL8973603 | 0.72 | TDP1 (0.45) | ALDH1A1HSD17B10TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL8973561 | 0.72 | HTR6 (0.47) | ALDH1A1HSD17B10MMP2PKMTDP1 | |
| SCHEMBL10680095 | 0.72 | HSD17B10 (0.42) | ALDH1A1HSD17B10TSHRMMP2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444546-B1 | Hydantoin derivatives for use as hypoglycemic and/or hypolipidemic agents | MOCHIDA PHARM CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-RE35279-E | ALDOSE REDUCTASE INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5202339-A | Hypoglycemic, hypolipedemic agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0305947-B1 | HYDANTOIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS THEIR USE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-29 | — | — | EP | disclosed |
| WO-1991012803-A1 | HYDANTOIN DERIVATIVES FOR USE AS HYPOGLYCEMIC AND/OR HYPOLIPIDEMIC AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-05 | — | — | WO | disclosed |
| EP-0444546-A1 | Hydantoin derivatives for use as hypoglycemic and/or hypolipidemic agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |
| US-5004751-A | Antidiabetic agents; aldoe reductase inhibitors | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-02 | — | — | US | disclosed |
| US-4914099-A | TREATMENT OR PREVENTION OF DIABETIC COMPLICATIONS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| WO-1989001934-A1 | HYDANTOIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-09 | — | — | WO | disclosed |
| EP-0305947-A1 | Hydantoin derivatives, process for their preparation and pharmaceutical compositions containing the same as well as their use | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-08 | — | — | EP | disclosed |