Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1347642 | 0.95 | PTGS2 (0.49) | PTGS2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9453031 | 0.94 | PTGS2 (0.50) | PTGS2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL7764834 | 0.90 | MEN1 (0.50) | PTGS2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL20787703 | 0.86 | TSHR (0.47) | PTGS2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL6675904 | 0.84 | MEN1 (0.42) | PTGS2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL3386571 | 0.82 | MEN1 (0.53) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2416893 | 0.81 | ALDH1A1 (0.40) | PTGS2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL11453241 | 0.80 | ALDH1A1 (0.47) | PTGS2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8324749 | 0.79 | ALDH1A1 (0.50) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL7458037 | 0.79 | CA2 (0.57) | KMT2AMEN1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335274-B1 | Formation of nitrophenyl ethers from polyols and nitroanisoles | DOW CHEMICAL CO (US) | 1996-03-13 | — | — | EP | disclosed |
| US-4960950-A | Formation of nitrophenyl ethers from polyols and nitroanisoles | THE DOW CHEMICAL COMPANY (US) | 1990-10-02 | — | — | US | disclosed |