SCHEMBL8973243

SCHEMBL8973243

O=C(O)C(CCC(Oc1ccccc1)Oc1ccccc1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARG P37231 17/20 0.45
PPARA Q07869 15/20 0.45
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.42
CYP2C9 P11712 1/20 0.42
PKM P14618 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29161839 0.77 HDAC3 (0.50) PPARAMTNR1AMTNR1BCYP1A2CYP2C19
SCHEMBL6438883 0.77 ALDH1A1 (0.46) PPARGPPARAMTNR1AMTNR1BGAA
SCHEMBL10585401 0.77 KMT2A (0.56) PPARGPPARAMTNR1AMTNR1BCYP1A2
SCHEMBL28444649 0.75 MTNR1A (0.44) PPARGPPARAMTNR1AMTNR1BCYP1A2
SCHEMBL1538040 0.75 ALOX15 (0.48) PPARGPPARAMTNR1AMTNR1BCYP1A2
SCHEMBL28371402 0.74 TDP1 (0.46) PPARGPPARAMTNR1AMTNR1BGAA
SCHEMBL28371401 0.74 TDP1 (0.46) PPARGPPARAMTNR1AMTNR1BGAA
SCHEMBL1805351 0.73 TDP1 (0.57) PPARGPPARAMTNR1AMTNR1BCYP1A2
SCHEMBL6463009 0.72 SLC6A4 (0.43) PPARGPPARAMTNR1AMTNR1B
SCHEMBL4370604 0.72 SLC6A4 (0.39) PPARGPPARAMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112384489-A Method for producing organic compound 尤尼吉可株式会社 2021-02-19 CN disclosed
EP-0699130-A1 MULTILAYERED POLYMER FILMS AND PROCESS FOR THE PREPARATION THEREOF NESTE OY (FI) 1996-03-06 EP disclosed
WO-1995023063-A1 MULTILAYERED POLYMER FILMS AND PROCESS FOR THE PREPARATION THEREOF NESTE OY (FI) 1995-08-31 WO disclosed
EP-0226361-A1 Electrically conductive resin composition POLYPLASTICS CO. LTD. (JP) 1987-06-24 EP disclosed