SCHEMBL8973284

SCHEMBL8973284

Nc1ccc2nc(C(CC(=O)O)C(O)=S)sc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
SMN1; SMN2 Q16637 6/20 0.42
MAPT P10636 11/20 0.42
ALDH1A1 P00352 7/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 5/20 0.42
KDM4E B2RXH2 4/20 0.42
HPGD P15428 4/20 0.42
GLA P06280 3/20 0.42
PKM P14618 2/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
NPC1 O15118 5/20 0.40
RAB9A P51151 5/20 0.40
GFER P55789 2/20 0.40
POLB P06746 2/20 0.40
MITF O75030 1/20 0.40
NFKB1 P19838 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8973276 0.90 SMN1; SMN2 (0.44) MEN1KMT2ASMN1; SMN2MAPTALDH1A1
SCHEMBL8972435 0.85 AKR1B1 (0.44) MEN1KMT2ASMN1; SMN2MAPTALDH1A1
SCHEMBL8971606 0.83 MAPT (0.52) MEN1KMT2ASMN1; SMN2MAPTALDH1A1
SCHEMBL8972422 0.82 RAB9A (0.47) MEN1KMT2ASMN1; SMN2MAPTALDH1A1
SCHEMBL8973017 0.81 PKM (0.51) MEN1KMT2ASMN1; SMN2MAPTALDH1A1
SCHEMBL9443152 0.81 LDHA (0.43) SMN1; SMN2MAPTLMNACA1CA2
SCHEMBL30944811 0.81 PKM (0.52) MEN1KMT2ASMN1; SMN2ALDH1A1HPGD
SCHEMBL402777 0.81 PKM (0.52) MEN1KMT2ASMN1; SMN2ALDH1A1HPGD
SCHEMBL9443182 0.81 ALDH1A1 (0.55) MEN1KMT2ASMN1; SMN2ALDH1A1GAA
SCHEMBL8973268 0.81 MEN1 (0.44) MEN1KMT2ASMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5549847-A STIRRING A FILTER CAKE OF CORROSION INHIBITOR WITH DISPERSANT AND THICKENER; STORAGE STABILITY CIBA-GEIGY CORPORATION (US) 1996-08-27 US disclosed
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
EP-0375614-B1 CORROSION-INHIBITING COATING COMPOSITIONS CIBA-GEIGY AG (CH) 1993-03-31 EP disclosed
US-5198482-A Benzothiazole carboxylic acid amine salt CIBA-GEIGY CORPORATION (US) 1993-03-30 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
EP-0375614-A1 Corrosion-inhibiting coating compositions CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed
US-4612049-A BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed