Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973450 | 0.88 | PKM (0.44) | MEN1KMT2APOLBHSD17B10ALDH1A1 | |
| SCHEMBL8973629 | 0.83 | HSD17B10 (0.53) | MEN1KMT2APOLBHSD17B10TDP1 | |
| SCHEMBL8973545 | 0.83 | HSD17B10 (0.41) | MEN1KMT2APOLBHSD17B10TDP1 | |
| SCHEMBL8789027 | 0.79 | PKM (0.59) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL8972857 | 0.78 | MEN1 (0.40) | MEN1KMT2APOLBHSD17B10ALDH1A1 | |
| SCHEMBL8973617 | 0.77 | PKM (0.41) | MEN1KMT2APOLBHSD17B10TDP1 | |
| SCHEMBL8973411 | 0.77 | PKM (0.52) | MEN1KMT2APOLBHSD17B10ALDH1A1 | |
| SCHEMBL8799258 | 0.77 | MEN1 (0.55) | MEN1KMT2APOLBHSD17B10ALDH1A1 | |
| SCHEMBL10675527 | 0.74 | KMT2A (0.54) | MEN1KMT2APOLBHSD17B10ALDH1A1 | |
| SCHEMBL8973561 | 0.73 | HTR6 (0.47) | MEN1KMT2APOLBHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35279-E | ALDOSE REDUCTASE INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5202339-A | Hypoglycemic, hypolipedemic agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0305947-B1 | HYDANTOIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS THEIR USE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5004751-A | Antidiabetic agents; aldoe reductase inhibitors | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-02 | — | — | US | disclosed |
| US-4914099-A | TREATMENT OR PREVENTION OF DIABETIC COMPLICATIONS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| WO-1989001934-A1 | HYDANTOIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-09 | — | — | WO | disclosed |
| EP-0305947-A1 | Hydantoin derivatives, process for their preparation and pharmaceutical compositions containing the same as well as their use | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-08 | — | — | EP | disclosed |