Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 4/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4373385 | 0.80 | ELANE (0.39) | MEN1KMT2APGR | |
| SCHEMBL4365447 | 0.78 | POLB (0.44) | HSD11B1MEN1KMT2ACYP3A4 | |
| SCHEMBL3585383 | 0.78 | LMNA (0.37) | MEN1KMT2A | |
| SCHEMBL8592625 | 0.78 | CA2 (0.43) | MEN1KMT2AKDM1ACHRNA7SLC6A3 | |
| SCHEMBL3590175 | 0.77 | DRD2 (0.41) | BACE1HSD11B1 | |
| SCHEMBL26354558 | 0.71 | ALDH1A1 (0.40) | — | |
| SCHEMBL12746552 | 0.70 | GLA (0.61) | BACE1HSD11B1KMT2A | |
| SCHEMBL13516187 | 0.69 | BACE1 (1.00) | BACE1HSD11B1KMT2A | |
| SCHEMBL29223628 | 0.68 | BACE1 (0.42) | BACE1HSD11B1MEN1KMT2AKDM1A | |
| SCHEMBL29223630 | 0.68 | BACE1 (0.42) | BACE1HSD11B1MEN1KMT2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703899-A1 | ARYLACETAMIDES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE AS FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029267-A1 | ARYLACETAMIDES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE AS FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1994-12-22 | — | — | WO | disclosed |