SCHEMBL8974647

SCHEMBL8974647

CCC[Si](C)(Cl)OC(C)=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8975138 0.82
SCHEMBL3096456 0.79 ALDH1A1 (0.35) ALDH1A1LMNAHSD17B10
SCHEMBL10773422 0.77 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10
SCHEMBL5359673 0.76 ALDH1A1 (0.36) ALDH1A1LMNAHSD17B10
SCHEMBL435046 0.76 ALDH1A1 (0.36) ALDH1A1LMNAHSD17B10
SCHEMBL229663 0.73 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10
SCHEMBL476034 0.73 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10
SCHEMBL706130 0.73 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10
SCHEMBL19302939 0.71 ALDH1A1 (0.36) ALDH1A1LMNAHSD17B10
SCHEMBL704137 0.71 ALDH1A1 (0.36) ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0509213-B1 Process for the simultaneous and continuous production of carbonyloxy silanes and of carboxylic acid chlorides HUELS CHEMISCHE WERKE AG (DE) 1996-04-10 EP disclosed
EP-0509213-A1 Process for the simultaneous and continuous production of carbonyloxy silanes and of carboxylic acid chlorides HÜLS AKTIENGESELLSCHAFT (DE) 1992-10-21 EP disclosed