Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.93 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.93 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.93 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.93 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.60 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.60 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM5C | P41229 | 3/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | KDM6B | O15054 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Ketoglutaric Acid SCHEMBL1131520 | 1.00 | EGLN1 (0.93) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL30208560 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL30029036 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL7400 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL17127347 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL932116 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL3776640 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL29783374 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL1428274 | 0.93 | EGLN1 (0.93) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL3184813 | 0.93 | EGLN1 (0.93) | EGLN1OR51E2MAPK1SLC13A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955139-B | Process for preparing alpha-ketoglutarate calcium | 庞塞迪利昂健康特定活动公司 | 2025-04-18 | — | — | CN | claimed |
| CN-117865790-A | Preparation method and purification method of alpha-ketoglutarate disodium | 张家港市华天药业有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-115721614-A | alpha-KG sustained release preparation and application thereof | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2023-03-03 | — | — | CN | claimed |
| CN-114105761-A | Synthesis process of alpha-ketoglutaric acid sodium salt | 广东派特埃尔生物科技有限公司 | 2022-03-01 | — | — | CN | claimed |
| EP-3856166-A1 | PROCESS OF MAKING CALCIUM ALPHA-KETOGLUTARATE | Ponce de Leon Health Designated Activity Company (IE) | 2021-08-04 | — | — | EP | claimed |
| CN-108378136-B | Low-salt quick-cooking fermented bean curd sauce and preparation method thereof | GUIZHOU UNIVERSITY (CN) | 2021-06-22 | — | — | CN | claimed |
| CN-112955139-A | Process for the preparation of calcium alpha-ketoglutarate | 庞塞迪利昂健康特定活动公司 | 2021-06-11 | — | — | CN | claimed |
| WO-2020068705-A1 | PROCESS OF MAKING CALCIUM ALPHA-KETOGLUTARATE | PONCE DE LEON HEALTH DESIGNATED ACTIVITY COMPANY (IE) | 2020-04-02 | — | — | WO | claimed |
| US-20170113086-A1 | METHODS AND SYSTEMS FOR NEUTRALIZATION OF HYDRAZINE | Hydrazine Neutralizing Solutions Inc. | 2017-04-27 | — | — | US | claimed |
| CN-105348877-A | Water-proofing agent for tunnel | CHUZHOU SIMAITE COMPOSITE MATERIAL CO LTD | 2016-02-24 | — | — | CN | claimed |
| CN-104830513-A | Semi-synthetic metal cutting fluid | YANTAI SHUNLONG CHEMICAL ENGINEERING TECHNOLOGY CO LTD | 2015-08-12 | — | — | CN | claimed |
| CN-104798866-A | Preservative agent for spraying surface of venison | YANTAI SHUNLONG CHEMICAL TECHNOLOGY CO LTD | 2015-07-29 | — | — | CN | claimed |
| CN-104450267-A | Apple detergent | XU YUWEN | 2015-03-25 | — | — | CN | claimed |
| CN-104177899-A | Fire retardant for car seat | MA XIAOQUAN | 2014-12-03 | — | — | CN | claimed |
| CN-121135524-B | Preparation method of nutrient solution for soilless culture of strawberries | 四川水利职业技术学院 | 2026-05-15 | — | — | CN | disclosed |
| CN-112955139-B | Process for preparing alpha-ketoglutarate calcium | 庞塞迪利昂健康特定活动公司 | 2025-04-18 | — | — | CN | disclosed |
| WO-2025034579-A1 | METHODS FOR PREPARATION OF BIOCOMPATIBLE SOLUTIONS WITH SABRE HYPERPOLARIZATION | VIZMA LIFE SCIENCES, INC. (US) | 2025-02-13 | — | — | WO | disclosed |
| US-5169780-A | Conversion to ketone in aqueous solution with amino acceptor and omega-amino acid acceptor; solvent extraction | CELGENE CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0404146-A2 | Enantiomeric enrichment and stereoselective synthesis of chiral amines | CELGENE CORPORATION (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4950606-A | CONTACTING IN AN AQUEOUS MEDIUM IN THE PRESENCE OF AN AMINO ACCEPTOR WITH AN OMEGA-AMINO ACID TRANSAMINASE TO CONVERT ONE OF AMINES TO KETONE | CELGENE CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |