Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.93 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.93 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.93 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.93 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.60 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.60 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM5C | P41229 | 3/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | KDM6B | O15054 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Ketoglutaric Acid SCHEMBL8974974 | 1.00 | EGLN1 (0.93) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL30208560 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL30029036 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL3776640 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL932116 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL7400 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL17127347 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL29783374 | 0.97 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL2823722 | 0.93 | EGLN1 (0.93) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL9782859 | 0.93 | EGLN1 (0.93) | EGLN1OR51E2MAPK1SLC13A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122081117-A | Method for producing single cell protein by utilizing mixed flora | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080382-A | Isosorbide type polycarbonate and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122036155-A | Composite material containing functional microorganisms and iron-doped carbon quantum dots, and preparation method and application thereof | 南京林业大学 | 2026-05-15 | — | — | CN | claimed |
| CN-121569905-A | Anti-aging composition for pets as well as application method and application thereof | 杭州泰鲁澳纽健康科技有限公司 | 2026-02-27 | — | — | CN | claimed |
| CN-119837187-A | Application of alpha-ketoglutaric acid in feed additive for relieving heat stress induced skeletal muscle development injury of offspring calves during pregnancy | 南京农业大学 | 2025-04-18 | — | — | CN | claimed |
| CN-119040110-A | Dry-type analysis reagent tablet for detecting glutamic-oxaloacetic transaminase | 乐凯医疗科技有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-118475682-A | Composition for animal cell culture | 味之素株式会社 | 2024-08-09 | — | — | CN | claimed |
| EP-3398594-B1 | COMPOSITIONS FOR IMPROVEMENT OF BRAIN FUNCTION | GRESPO AB (SE) | 2024-07-10 | — | — | EP | claimed |
| CN-114105761-B | Synthesis process of alpha-ketoglutarate sodium salt | 广东派特埃尔生物科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-118146083-A | Preparation method of alpha-ketoglutaric acid and derivatives thereof | 中国农业科学院饲料研究所 | 2024-06-07 | — | — | CN | claimed |
| WO-2009005464-A1 | NEW USE OF KNOWN PHARMACOLOGICALLY ACTIVE CHEMICAL COMPOUNDS | ENTRESS AB (SE) | 2009-01-08 | — | — | WO | claimed |
| WO-2008118032-A1 | COMPOSITIONS FOR TREATING INTOXICATIONS COMPRISING A PHΞNOTHIAZINE COMPOUND | RESEARCH INSTITUTE OF HYGIENE, OCCUPATIONAL PATHOLOGY AND HUMAN ECOLOGY (RIHOPHE) (RU) | 2008-10-02 | — | — | WO | claimed |
| WO-2008058993-A2 | USE OF ALPHA KETOGLUARIC ACID FOR THE TREATMENT OF INFECTION WITH H. PYLORI | ENTRESS AB (SE) | 2008-05-22 | — | — | WO | claimed |
| US-20080027139-A1 | Use of Alpha-Ketoglutarate and Related Compounds | PROTISTA BIOTECHNOLOGY AB (SE) | 2008-01-31 | — | — | US | claimed |
| CN-101105491-A | Dry chemical test paper for quantitatively determining human alanine aminotransferase | SHANGHAI KEHUA BIOENGINEERING (CN) | 2008-01-16 | — | — | CN | claimed |
| CN-1912132-A | Composition for measuring glucose having improved substrate specificity | TOYO BOSEKI (JP) | 2007-02-14 | — | — | CN | claimed |
| CN-1546683-A | Aspartic transaminase mitochondrion isozyme m type measurement method | 上海北加生化试剂有限公司 | 2004-11-17 | — | — | CN | claimed |
| EP-0169055-B1 | POLYMERIC SINGLE LAYER ANALYTICAL ELEMENT | TECHNICON INSTRUMENTS CORPORATION(a Delaware corporation) (US) | 1991-08-14 | — | — | EP | claimed |
| US-4371618-A | Process for enzymatically producing L-carnitine | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1983-02-01 | — | — | US | claimed |
| US-3953294-A | STORAGE STABLE REAGENT CONTAINING NONIONIC SURFACTANT | MALLINCKRODT, INC. (US) | 1976-04-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027139-A1 | Use of Alpha-Ketoglutarate and Related Compounds | GLUL, GLS, TGM1 | EGLN1 428/4885OR51E2 4713/4885MAPK1 2966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.