SCHEMBL8975005

SCHEMBL8975005

CCOC(=O)Nc1ccc(N(CC)CC)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.75
RAB9A P51151 5/20 0.58
NPC1 O15118 4/20 0.58
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
NOX1 Q9Y5S8 2/20 0.58
HPGD P15428 3/20 0.58
CRHBP P24387 1/20 0.58
CRHR2 Q13324 1/20 0.58
MTNR1A P48039 1/20 0.56
MTNR1B P49286 1/20 0.56
NPY1R P25929 1/20 0.56
NPY2R P49146 1/20 0.56
MCL1 Q07820 2/20 0.55
POLB P06746 1/20 0.55
GAA P10253 1/20 0.55
ALDH1A1 P00352 4/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
MAPK1 P28482 2/20 0.55
KDM4E B2RXH2 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565510 0.87 RAB9A (0.71) MAPTRAB9ANPC1HPGDCRHBP
SCHEMBL29565802 0.84 MAPT (0.67) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL11134313 0.83 MAPK1 (0.61) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL9146676 0.82 LMNA (0.68) MAPTRAB9ANPC1HPGDCRHBP
SCHEMBL1719720 0.82 SMN1; SMN2 (0.71) MAPTRAB9ANPC1HPGDCRHBP
SCHEMBL7565512 0.82 RAB9A (0.70) MAPTRAB9ANPC1HPGDCRHBP
SCHEMBL11790359 0.82 RAB9A (0.65) MAPTRAB9ANPC1HPGDCRHBP
SCHEMBL8975219 0.82 NOX1 (0.66) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL19390510 0.80 SMN1; SMN2 (0.67) MAPTRAB9ANPC1KMT2AMEN1
SCHEMBL352811 0.80 RAB9A (0.63) MAPTRAB9ANPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4647625-A Process for modifying conjugated diene polymers NIPPON ZEON CO., LTD. (JP) 1987-03-03 US claimed
US-8367775-B2 Modified conjugated diene-vinyl aromatic copolymer and method for manufacturing the same CHI MEI CORPORATION (TW) 2013-02-05 US disclosed
US-20120172526-A1 MODIFIED CONJUGATED DIENE-VINYL AROMATIC COPOLYMER AND METHOD FOR MANUFACTURING THE SAME CHI MEI CORPORATION (TW) 2012-07-05 US disclosed
EP-0512477-B1 Thermal imaging methods and materials POLAROID CORP (US) 1996-03-20 EP disclosed
US-5350870-A Leuco dyes POLAROID CORPORATION (US) 1994-09-27 US disclosed
US-5236884-A Leuco dye containing leaving group and migratable acyl group, reduced bubble formation POLAROID CORPORATION (US) 1993-08-17 US disclosed
EP-0512477-A1 Thermal imaging methods and materials POLAROID CORPORATION (US) 1992-11-11 EP disclosed
US-4950719-A LOW TEMPERATURE VIBRATION INSULATOR NIPPON ZEON CO., LTD. (JP) 1990-08-21 US disclosed
EP-0150479-B1 PROCESS FOR MODIFYING CONJUGATED DIENE POLYMERS NIPPON ZEON CO., LTD. (JP) 1990-06-13 EP disclosed
US-4647625-A Process for modifying conjugated diene polymers NIPPON ZEON CO., LTD. (JP) 1987-03-03 US disclosed
EP-0150479-A2 Process for modifying conjugated diene polymers NIPPON ZEON CO., LTD. (JP) 1985-08-07 EP disclosed