Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563661 | 1.00 | LMNA (0.56) | LMNAMAPK1GSK3BCA2CA1 | |
| SCHEMBL11852166 | 0.94 | LMNA (0.50) | LMNAMAPK1GSK3BCA2CA1 | |
| SCHEMBL275597 | 0.82 | LMNA (0.79) | LMNAMAPK1L3MBTL1TSHR | |
| SCHEMBL19002291 | 0.82 | GSK3B (0.44) | GSK3BCA2CA1KDM4EGAA | |
| SCHEMBL29001006 | 0.81 | HPGD (0.44) | GSK3BCA2CA1KDM4EGAA | |
| SCHEMBL11219485 | 0.81 | GSK3B (0.47) | GSK3BCA2CA1KDM4EGAA | |
| SCHEMBL14965641 | 0.80 | MAPT (0.43) | LMNAGSK3BCA2CA1KDM4E | |
| SCHEMBL29902494 | 0.79 | LMNA (0.56) | LMNAMAPK1CA2CA1L3MBTL1 | |
| SCHEMBL2575820 | 0.78 | PTGS2 (0.55) | LMNAGSK3BCA2CA1KDM4E | |
| SCHEMBL8223856 | 0.78 | PTGS2 (0.55) | LMNAGSK3BCA2CA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703899-A1 | ARYLACETAMIDES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE AS FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029267-A1 | ARYLACETAMIDES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE AS FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1994-12-22 | — | — | WO | disclosed |