Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000484 | 0.81 | NR1I2 (0.53) | MAPTL3MBTL1GSK3BKDM4EGAA | |
| SCHEMBL31037724 | 0.81 | NR1I2 (0.53) | MAPTL3MBTL1GSK3BKDM4EGAA | |
| SCHEMBL3696286 | 0.81 | CA2 (0.52) | GSK3BCA2CA1CA12CA3 | |
| SCHEMBL2563661 | 0.80 | LMNA (0.56) | MAPTL3MBTL1GSK3BKDM4EGAA | |
| SCHEMBL8975203 | 0.80 | LMNA (0.56) | MAPTL3MBTL1GSK3BKDM4EGAA | |
| SCHEMBL14965675 | 0.79 | GRM4 (0.50) | GSK3BKDM4ELMNAADRA2BADRA1D | |
| SCHEMBL11219485 | 0.78 | GSK3B (0.47) | MAPTL3MBTL1GSK3BKDM4EGAA | |
| Cadaverine Tartrate SCHEMBL27756099 | 0.78 | TSHR (0.61) | MAPTL3MBTL1GSK3BKDM4ECA2 | |
| SCHEMBL11603519 | 0.78 | TSHR (0.54) | KDM4ECA2CA12CA3CA6 | |
| Cadaverine Tartrate SCHEMBL27756100 | 0.78 | TSHR (0.61) | MAPTL3MBTL1GSK3BKDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9505733-B2 | Single step enantioselective process for the preparation of 3-substituted chiral phthalides | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-11-29 | — | — | US | disclosed |
| US-20150299154-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-10-22 | — | — | US | disclosed |
| US-9073887-B2 | Single step enantioselective process for the preparation of 3-substituted chiral phthalides | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | disclosed |
| US-20140330027-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-11-06 | — | — | US | disclosed |
| WO-2013072830-A9 | A SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-02-20 | — | — | WO | disclosed |
| WO-2013072830-A1 | A SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330027-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | PPOX, NFE2L2, CBR1 | MAPT 2273/4885L3MBTL1 4397/4885GSK3B 1020/4885 |
| US-20150299154-A1 | SINGLE STEP ENANTIOSELECTIVE PROCESS FOR THE PREPARATION OF 3-SUBSTITUTED CHIRAL PHTHALIDES | PPOX, NFE2L2, CBR1 | MAPT 2273/4885L3MBTL1 4397/4885GSK3B 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.