Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957378 | 0.91 | CYP2C19 (0.64) | TSHRCYP19A1CYP2C19ESR1KMT2A | |
| SCHEMBL4424044 | 0.88 | TSHR (0.75) | TSHRCYP19A1CYP2C19ESR1KMT2A | |
| SCHEMBL11814380 | 0.87 | CYP19A1 (0.47) | TSHRCYP19A1CYP2C19ESR1KMT2A | |
| SCHEMBL43183 | 0.84 | TSHR (0.74) | TSHRCYP2C19KMT2AALDH1A1NR1H2 | |
| SCHEMBL11874481 | 0.83 | ESR1 (0.66) | CYP19A1ESR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL355040 | 0.81 | TSHR (0.71) | TSHRCYP2C19KMT2AALDH1A1NR1H2 | |
| Hydrochloric Acid SCHEMBL2139953 | 0.81 | TSHR (0.71) | TSHRCYP2C19KMT2AALDH1A1NR1H2 | |
| SCHEMBL10702263 | 0.80 | TSHR (0.75) | TSHRCYP2C19KMT2AMEN1ALDH1A1 | |
| Nitrogen SCHEMBL4599425 | 0.79 | TSHR (0.68) | TSHRCYP2C19KMT2AALDH1A1NR1H2 | |
| SCHEMBL4427377 | 0.79 | CRHBP (0.57) | TSHRCYP19A1ESR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457485-B1 | Nonlinear optical devices and methods for making them | AT & T CORP (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5119228-A | Nonlinear optical devices | AT&T BELL LABORATORIES (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0457485-A2 | Nonlinear optical devices and methods for making them | AT&T Corp. (US) | 1991-11-21 | — | — | EP | disclosed |
| US-5045364-A | Nonlinear optical devices and methods | AT&T BELL LABORATORIES (US) | 1991-09-03 | — | — | US | disclosed |