Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 8/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789315 | 0.97 | DRD2 (0.37) | DRD2DRD4DRD3HTR2CHTR2A | |
| SCHEMBL14704910 | 0.91 | HTR2C (0.37) | DRD2DRD4DRD3HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL27671598 | 0.83 | HTR6 (0.33) | DRD2DRD4DRD3HTR2CHTR2A | |
| SCHEMBL308810 | 0.80 | — | — | |
| SCHEMBL28153662 | 0.80 | DRD2 (0.41) | DRD2DRD4DRD3HTR2CHTR2A | |
| SCHEMBL260416 | 0.75 | DRD2 (0.42) | DRD2DRD4DRD3PKMALDH1A1 | |
| SCHEMBL5599984 | 0.72 | DRD2 (0.41) | DRD2DRD4DRD3PKMALDH1A1 | |
| SCHEMBL5601933 | 0.72 | DRD2 (0.41) | DRD2DRD4DRD3PKMALDH1A1 | |
| SCHEMBL5600054 | 0.72 | DRD2 (0.41) | DRD2DRD4DRD3PKMALDH1A1 | |
| SCHEMBL1901033 | 0.72 | DRD2 (0.41) | DRD2DRD4DRD3PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482602-B | Quaternary ammonium amide and/or ester salts | THE LUBRIZOL CORP. (US) | 2015-07-29 | — | — | CN | claimed |
| CN-103980183-A | Substituted bismuth (III) dithiopiperdylcarbamate complex and preparation method and application thereof in preparing anti-tumor medicines | TIANJIN BOMEIKAITAI BIOPHARMACEUTICAL TECHNOLOGY CO LTD | 2014-08-13 | — | — | CN | claimed |
| CN-103102436-A | Synthesis of a liquid polymer and a functionalized polymer | BRIDGESTONE CORP | 2013-05-15 | — | — | CN | claimed |
| CN-102482602-A | Quaternary ammonium amide and/or ester salts | LUBRIZOL CORP | 2012-05-30 | — | — | CN | claimed |
| CN-101821297-A | Synthesis of liquid polymers and functionalized polymers | BRIDGESTONE CORP | 2010-09-01 | — | — | CN | claimed |
| CN-100575341-C | The derivative of tetrahydro-indolone and the derivative of tetrahydro-indazolone and their application | GUOYAO LONGLI BIOLOG MEDICAL NEW TECHNOLOGY CO LTD BEIJING | 2009-12-30 | — | — | CN | claimed |
| CN-101484424-A | Therapeutic compounds | HELICON THERAPEUTICS INC (US) | 2009-07-15 | — | — | CN | claimed |
| CN-101481353-A | Tetrahydro indazolone or tetrahydro indolone substituted indazole derivative and salt thereof | BEIJING GYLONGLY BIOMEDTECH LT (CN) | 2009-07-15 | — | — | CN | claimed |
| CN-1896060-A | Tetrahydro-indolone and tetrahydro-indazolone derivatives and their use | GUOYAO LONGLI BIOLOG MEDICAL N (CN) | 2007-01-17 | — | — | CN | claimed |
| EP-4413985-B1 | PHARMACEUTICAL COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2026-05-06 | — | — | EP | disclosed |
| EP-4714446-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2026-03-25 | — | — | EP | disclosed |
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| EP-4413985-A2 | PHARMACEUTICAL COMPOUNDS | Nxera Pharma UK Limited (GB) | 2024-08-14 | — | — | EP | disclosed |
| WO-2024153161-A1 | SUBSTITUTED AMINOPYRIMIDINE MACROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND MEDICAL USES THEREOF | 江苏恒瑞医药股份有限公司 | 2024-07-25 | — | — | WO | disclosed |
| WO-1995010519-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1995-04-20 | — | — | WO | disclosed |
| CN-1017800-B | TRICYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 1992-08-12 | — | — | CN | disclosed |
| US-4864023-A | MICROBIOCIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4801584-A | ANTIMICROBIAL | HOFFMANN-LA ROCHE INC. (US) | 1989-01-31 | — | — | US | disclosed |
| CN-87106838-A | Tricyclic compound | — | 1988-05-11 | — | — | CN | disclosed |
| EP-0259804-A2 | Pyrido[3,2,1-ij]-1,3,4-benzoxadiazine derivatives, process for their preparation, resulting pharmaceutical preparations and intermediates for use in the process | F. HOFFMANN-LA ROCHE AG (CH) | 1988-03-16 | — | — | EP | disclosed |