Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360768 | 0.85 | KDM4E (0.54) | POLBGAAKDM4ESMN1; SMN2AR | |
| SCHEMBL18159867 | 0.85 | POLB (0.60) | POLBGAAKDM4EARMAPT | |
| SCHEMBL20511067 | 0.85 | KDM4E (0.54) | POLBGAAKDM4ESMN1; SMN2AR | |
| SCHEMBL9745662 | 0.85 | SMN1; SMN2 (0.58) | POLBGAAKDM4ESMN1; SMN2AR | |
| SCHEMBL9745478 | 0.85 | SMN1; SMN2 (0.58) | POLBGAAKDM4ESMN1; SMN2AR | |
| SCHEMBL9359794 | 0.85 | KDM4E (0.54) | POLBGAAKDM4ESMN1; SMN2AR | |
| SCHEMBL22169508 | 0.84 | POLB (1.00) | POLBGAAARMAPTNPC1 | |
| SCHEMBL669346 | 0.84 | SMN1; SMN2 (0.57) | POLBGAAKDM4ESMN1; SMN2AR | |
| SCHEMBL7121279 | 0.84 | POLB (0.51) | POLBGAAKDM4ESMN1; SMN2AR | |
| SCHEMBL29800655 | 0.84 | POLB (0.51) | POLBGAAKDM4ESMN1; SMN2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117597147-A | Inhibitors of ubiquitin-specific peptidase 22 (USP 22) and uses thereof for the treatment of diseases and disorders | 西北大学 | 2024-02-23 | — | — | CN | claimed |
| CN-117597147-A | Inhibitors of ubiquitin-specific peptidase 22 (USP 22) and uses thereof for the treatment of diseases and disorders | 西北大学 | 2024-02-23 | — | — | CN | disclosed |
| EP-0398620-B1 | Poly(oxyalkylene) modified phthalocyanine colorants | MILLIKEN RES CORP (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5149800-A | For natural or synthetic resins, especially polyolefins and polyurethane foams | MILLIKEN RESEARCH CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| US-5135972-A | For polymeric substrates | MILLIKEN RESEARCH CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0398620-A2 | Poly(oxyalkylene) modified phthalocyanine colorants | MILLIKEN RESEARCH CORPORATION (US) | 1990-11-22 | — | — | EP | disclosed |