Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.71 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.71 |
| ▸ | ADK | P55263 | 5/20 | 0.65 |
| ▸ | HTR2B | P41595 | 5/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.62 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.52 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327965 | 0.89 | ADK (0.69) | ADORA3ADORA2AADORA1ADKHTR2B | |
| SCHEMBL8332977 | 0.88 | ADORA3 (0.69) | ADORA3ADORA2AADORA1ADKHTR2B | |
| SCHEMBL8975362 | 0.86 | ADORA3 (0.66) | ADORA3ADORA2AADORA1ADKHTR2B | |
| SCHEMBL8331350 | 0.84 | ADK (0.69) | ADORA3ADORA2AADORA1ADKHTR2B | |
| SCHEMBL6236072 | 0.84 | ADK (0.69) | ADORA3ADORA2AADORA1ADKHTR2B | |
| SCHEMBL6762195 | 0.83 | ADORA3 (1.00) | ADORA3ADORA2AADORA1SLC29A1TP53 | |
| SCHEMBL8975011 | 0.81 | ADORA3 (0.66) | ADORA3ADORA2AADORA1ADKHTR2B | |
| SCHEMBL7070066 | 0.79 | ADK (0.79) | ADORA3ADKHTR2BSIGMAR1TMEM97 | |
| SCHEMBL31617931 | 0.79 | ADK (1.00) | ADKSLC29A1TP53 | |
| SCHEMBL17800832 | 0.79 | ADK (1.00) | ADKSLC29A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506347-A | ADENOSINE KINASE INHIBITOR | GENSIA, INC. (US) | 1996-04-09 | — | — | US | disclosed |