Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | CCKAR | P32238 | 3/20 | 0.52 |
| ▸ | CCKBR | P32239 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975338 | 0.96 | NPY1R (0.55) | OPRD1OPRM1 | |
| SCHEMBL34462106 | 0.87 | MME (0.54) | OPRD1OPRM1 | |
| SCHEMBL8975655 | 0.87 | NPY4R (0.67) | — | |
| SCHEMBL17553593 | 0.86 | REN (0.53) | OPRD1OPRM1 | |
| SCHEMBL2064604 | 0.86 | NPY4R (0.58) | OPRD1OPRM1 | |
| SCHEMBL2064607 | 0.86 | NPY4R (0.58) | OPRD1OPRM1 | |
| SCHEMBL11042205 | 0.86 | OPRK1 (0.53) | — | |
| SCHEMBL11043731 | 0.86 | OPRK1 (0.53) | — | |
| SCHEMBL11044131 | 0.86 | OPRK1 (0.53) | — | |
| SCHEMBL11045742 | 0.86 | OPRK1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350221-B1 | Dermorphin analogs, their methods of preparation, pharmaceutical compositions, and methods of therapeutic treatment using the same | ASTRA AB (SE) | 1996-04-17 | — | — | EP | disclosed |
| US-5312899-A | Dermorphin analogs | BIOCHEM PHARMA, INC. (CA) | 1994-05-17 | — | — | US | disclosed |