Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28812389 | 0.80 | ABCB1 (0.55) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL29738645 | 0.78 | NPC1 (0.64) | KMT2ANPC1ALDH1A1RAB9ACTNNB1 | |
| SCHEMBL878658 | 0.78 | NPC1 (0.64) | KMT2ANPC1ALDH1A1RAB9ACTNNB1 | |
| SCHEMBL8975637 | 0.77 | SLC6A3 (0.56) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL7645232 | 0.77 | KDM4E (0.58) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL3029800 | 0.77 | HCRTR1 (0.62) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL12572402 | 0.75 | PTGS2 (0.65) | ABCB1KDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL13990159 | 0.74 | L3MBTL1 (0.52) | ABCB1TSHRHSD17B10KMT2AALDH1A1 | |
| SCHEMBL6737969 | 0.74 | CTNNB1 (0.61) | ABCB1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL13020272 | 0.74 | TSHR (0.47) | ABCB1KDM4ETSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543919-B1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES | SEARLE & CO (US) | 1996-04-10 | — | — | EP | claimed |