Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578299 | 0.84 | SLC6A3 (0.57) | SLC6A3TSHRLMNAL3MBTL1HSD17B10 | |
| SCHEMBL24271236 | 0.82 | SLC6A3 (0.56) | SLC6A3TSHRLMNAL3MBTL1HSD17B10 | |
| Methyl 2-Methoxybenzoate SCHEMBL196037 | 0.79 | TSHR (0.69) | SLC6A3TSHRLMNAL3MBTL1HSD17B10 | |
| Methyl 2-Methoxybenzoate SCHEMBL29702077 | 0.79 | TSHR (0.69) | SLC6A3TSHRLMNAL3MBTL1HSD17B10 | |
| SCHEMBL2441955 | 0.79 | SLC6A3 (0.65) | SLC6A3TSHRLMNAL3MBTL1HSD17B10 | |
| SCHEMBL18155070 | 0.79 | LIG1 (0.51) | LMNAHSD17B10KMT2AKDM4EMAPT | |
| SCHEMBL3307629 | 0.78 | NPC1 (0.53) | SLC6A3TSHRLMNAL3MBTL1HSD17B10 | |
| SCHEMBL2127765 | 0.78 | TSHR (0.55) | SLC6A3TSHRLMNAHSD17B10SLC6A4 | |
| SCHEMBL8975646 | 0.77 | ABCB1 (0.46) | TSHRHSD17B10ALDH1A1KMT2AKDM4E | |
| SCHEMBL28432969 | 0.77 | KMT2A (0.63) | SLC6A3TSHRLMNAL3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543919-B1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES | SEARLE & CO (US) | 1996-04-10 | — | — | EP | claimed |